Merck, 1012123-200MG, Adenosine

General description
Adenosine is a nucleoside formed by the attachment of adenine to a ribose sugar. The USP Adenosine standard provides a reference for the quality and purity of adenosine used in pharmaceutical formulations and research applications, ensuring consistency in its therapeutic and experimental use.
The USP biologics oligonucleotides category includes a variety of synthetic nucleic acid sequences that are essential in research, diagnostics, and therapeutic applications. These oligonucleotides play crucial roles in molecular biology, including gene expression regulation, antisense therapy, and RNA interference. The USP provides comprehensive standards, reference materials, and analytical procedures to ensure the identity, quality, purity, and consistency of oligonucleotide products throughout their lifecycle.
The United States Pharmacopeia (USP) provides quality standards for biologics to ensure their safety, efficacy, and quality throughout the manufacturing process. These standards assist manufacturers in adhering to regulatory requirements and help safeguard public health by reducing risks associated with biologics.

Application
Adenosine USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.
Also, for use with USP monographs such as:
Adenosine Injection
Heparin Sodium

Biochem/physiol Actions
Endogenous neurotransmitter at adenosine receptors. Cardioprotective effects may relate to activation of A1 adenosine receptors. The antiplatelet and anti−inflammatory actions of adenosine appear to be mediated via the A2 adenosine receptor. In contrast, adenosine appears to be a pro-inflammatory mediator in asthma and chronic obstructive pulmonary disease (COPD).
Endogenous neurotransmitter. Cardioprotective effects may relate to activation of A1 adenosine receptors. The antiplatelet and anti−inflammatory actions of adenosine appear to be mediated via the A2 adenosine receptor. In contrast, adenosine appears to be a pro-inflammatory mediator in asthma and chronic obstructive pulmonary disease (COPD).
Analysis Note
These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.
Other Notes
Sales restrictions may apply.
This product is part of USP Biologics Program.