Merck, 1020390050, Cesium chloride

Application

• Optimizing high-throughput viral vector characterization with density gradient equilibrium analytical ultracentrifugation.: This study utilizes cesium chloride for optimizing high-throughput characterization of viral vectors using density gradient equilibrium analytical ultracentrifugation, enhancing the efficiency and accuracy of viral vector analysis. (Sternisha et al., 2023).


• Mammalian Reoviruses: Propagation, Quantification, and Storage.: Cesium chloride is used in this study to facilitate the propagation, quantification, and storage of mammalian reoviruses, contributing to better handling and study of these viruses in research settings. (Coombs, 2023).


• Large-scale purification of functional AAV particles packaging the full genome using short-term ultracentrifugation with a zonal rotor.: This paper discusses the large-scale purification of adeno-associated virus particles using cesium chloride in ultracentrifugation, which is crucial for gene therapy applications. (Wada et al., 2023).

Analysis Note
Purity (metallic): ≥ 99.995 %
Assay (argentometric): ≥ 99.5 %
Specific absorbance (260 nm; 50 %; 1 cm; water): ≤ 0.020
Specific absorbance (280 nm; 50 %; 1 cm; water): ≤ 0.020
Phosphate (PO₄): ≤ 10 ppm
Sulfate (SO₄): ≤ 20 ppm
Total nitrogen (N): ≤ 10 ppm
Al (Aluminium): ≤ 0.05 ppm
B (Boron): ≤ 0.05 ppm
Ba (Barium): ≤ 2.0 ppm
Ca (Calcium): ≤ 0.50 ppm
Cd (Cadmium): ≤ 0.005 ppm
Ce (Cerium): ≤ 0.005 ppm
Co (Cobalt): ≤ 0.005 ppm
Cr (Chromium): ≤ 0.005 ppm
Cu (Copper): ≤ 0.005 ppm
Eu (Europium): ≤ 0.005 ppm
Fe (Iron): ≤ 0.020 ppm
K (Potassium): ≤ 2 ppm
La (Lanthanum): ≤ 0.005 ppm
Li (Lithium): ≤ 0.2 ppm
Mg (Magnesium): ≤ 0.10 ppm
Mn (Manganese): ≤ 0.010 ppm
Na (Sodium): ≤ 4.0 ppm
Ni (Nickel): ≤ 0.020 ppm
Pb (Lead): ≤ 0.030 ppm
Rb (Rubidium): ≤ 5 ppm
Sc (Scandium): ≤ 0.005 ppm
Sm (Samarium): ≤ 0.005 ppm
Sr (Strontium): ≤ 0.20 ppm
Tl (Thallium): ≤ 0.20 ppm
Y (Yttrium): ≤ 0.005 ppm
Yb (Ytterbium): ≤ 0.005 ppm
Zn (Zinc): ≤ 0.020 ppm
Legal Information
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