Merck, 1086200-40MG, Calcitonin salmon

General description
Calcitonin salmon is a 32-amino acid peptide used therapeutically to regulate calcium homeostasis in conditions such as osteoporosis and Paget′s disease. It exerts its effect by directly inhibiting osteoclast activity. The USP reference standard supports bioidentity testing and analytical method validation.
The USP biologics peptides category encompasses a diverse range of therapeutic peptides that are essential in managing various medical conditions. These peptides, typically consisting of amino acid sequences of 40 residues or less, are critical for the development of high-quality medicines. The USP provides comprehensive standards, reference materials, and analytical procedures to ensure the identity, quality, purity, and consistency of peptide therapeutics throughout their lifecycle.
The United States Pharmacopeia (USP) provides quality standards for biologics to ensure their safety, efficacy, and quality throughout the manufacturing process. These standards assist manufacturers in adhering to regulatory requirements and help safeguard public health by reducing risks associated with biologics.

Application
Calcitonin salmon USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
Calcitonin Salmon Injection
Calcitonin Salmon Nasal Solution

Biochem/physiol Actions
Hypocalcemic hormone produced by the parafollicular C cells of the thyroid or by the ultimobranchial bodies of nonmammalian vertebrates. Decreases blood calcium and phosphate due to inhibition of resorption by osteoblasts and osteocytes.
Analysis Note
These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.
Other Notes
32 amino acid polypeptide, 8 of which are conserved across all species.
Sales restrictions may apply.
This product is part of the USP Biologics program.