| UNSPSC Code | 41115711 |
|---|---|
| Quality Level | 400 |
| ligand | (Sulfoisobutyl) |
| sterility | sterile (Caustic Stable) |
| product line | Eshmuno® |
| form | resin |
| specific analyte(s) | MAbs |
| parameter | 400 cm/hr flow rate |
| matrix active group | polymer, polyvinyl ether |
| mean particle size | 50 μm |
| capacity | 70 mg binding capacity (lysozyme/ml of resin) |
| transition temp | flash point 35 °C |
| separation technique | strong cation exchange |
| storage temp. | 2-30°C |
Answer:It is a strong cation-exchange resin designed for flow-through aggregate removal.
Answer:The mean particle size is approximately 50 µm.
Answer:This configuration contains 5 L of resin.
Eshmuno® CP-FT Resin is used for flow-through removal of monoclonal-antibody aggregates during downstream purification. The strong cation-exchange resin uses a sulfoisobutyl ligand on a rigid polyvinyl-ether polymer matrix with a mean particle size of approximately 50 µm. It is designed for frontal chromatography in which the desired antibody product passes through while aggregate species are preferentially retained. The resin supports flow rates up to approximately 400 cm/h and a maximum pressure of 8 bar, enabling high-throughput process operation. A representative binding capacity of about 70 mg lysozyme per mL of resin reflects the high-capacity ion-exchange surface. The material is caustic stable and chemically robust, supporting sanitization and repeated process use. This configuration contains 5 L and is intended for process-scale biopharmaceutical chromatography.
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