Merck, 1370489050, D-(+)-Glucose

Name: D-(+)-Glucose
Brand: Merck
SKU: 1370489050

Size:50 kg, Dextrose, anhydrous EMPROVE® EXPERT Ph Eur, BP, USP

Catalog Number: 1370489050

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Category

Monosaccharides

Pack Size50 kg

TagsCell Culture & Analysis Cell Culture Supplements & Reagents Bioprocessing Recombinant Supplements

CollectionsMerck Cell Culture Supplements & Reagents: Complete Solutions for Research & Bioproduction Merck Roche Life Science Products for PCR, RT‑PCR & Nucleic Acid Purification

Description

General description
Our SAFC® portfolio of high-quality products for biopharmaceutical processing withstands strict quality control procedures and is produced according to MQ-500 requirements as defined by the M-Clarity program.

M-Clarity Program

As part of our EMPROVE® Program, our raw materials are offered with EMPROVE® Dossiers which provide comprehensive, up-to-date documentation to help you navigate regulatory challenges, manage risks, and improve your manufacturing processes.

Our comprehensive portfolio of upstream process chemicals not only provides biopharmaceutical manufacturers with high-quality raw materials for production of classical and novel therapies, but also helps them get to market faster and simplify regulatory challenges. Trust us to deliver supply chain transparency and reliable sourcing around the globe, streamlining your product qualification with best-in-class regulatory support and service.
Analysis Note
Assay (calc. on anhydrous substance): 97.5 - 102.0 %
Identity (IR): passes test
Identity (spec. rotation calc. on anhydrous substance): passes test
Identity (HPLC): passes test
Identity (water): passes test
Appearance of solution: passes test
Color and clarity of solution: passes test
Titrable acid: ≤ 0.002 meq/g
Conductivity: ≤ 20 µS/cm
Spec. rotation (α25/D): 52.5 - 53.0 °
In water insoluble matter: ≤ 0.005 %
Chloride (Cl): ≤ 0.01 %
Sulfate (SO₄): ≤ 0.005 %
Heavy metals (as Pb): ≤ 5 ppm
Fe (Iron): ≤ 5 ppm
Related substances [sum of impurities A (maltose) and B (isomaltose)!: ≤ 0.4 %
Related substances [Impurity C (maltotriose)!: ≤ 0.2 %
Related substances [Impurity D (fructose)!: ≤ 0.15 %
Related substances (unspecified impurities): ≤ 0.10 %
Related substances (Sum of all impurities): ≤ 0.5 %
Dextrin: passes test
Soluble starch, sulfite: ≤ 15 ppm
Starch: passes test
Residual solvents (ICH Q3C): excluded by the manufacturing process
Loss on drying (105 °C): ≤ 0.2 %
Water (according to Karl Fischer): ≤ 1.0 %
Sulfated ash (600 °C): ≤ 0.02 %
Microbiological purity(Total aerobic microbial count (TAMC)): ≤ 100 CFU/g
Microbiological purity(Total yeast and mould count (TYMC)): ≤ 100 CFU/g
Bile tolerant Gram negative Bacteria(absent in 1 g): passes test
Escherichia coli (absent in 1 g): passes test
Pseudomonas aeruginosa (absent in 1 g): passes test
Staphylococcus aureus (absent in 1 g): passes test
Candida albicans (absent in 1 g): passes test
Salmonella ssp (absent in 10 g): passes test
Endotoxins: ≤ 10 I.U./g
Elemental impurity specifications have been set considering ICH Q3D (Guideline for Elemental Impurities). Class 1-3 elements are not likely to be present above the ICH Q3D option 1 limit, unless specified and indicated (*).

Corresponds to Ph Eur,BP,USP,ACS
Legal Information
Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Specifications

General

UNSPSC Code	12352201
EC Index Number	200-075-1
Beilstein/REAXYS Number	1724615
grade	ACS reagent
agency	BP
product line	EMPROVE® EXPERT
form	solid
autoignition temp.	500 °C
potency	25800 mg/kg LD50, oral (Rat)
Quality Level	500
InChI	1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5-,6+/m1/s1
SMILES string	OC[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@@H]1O
InChI key	WQZGKKKJIJFFOK-DVKNGEFBSA-N
mp	150-152 °C (lit.)
solubility	470 g/L
bulk density	630 kg/m3
application(s)	parenterals
storage temp.	15-25°C

FAQs

Question: Is this glucose anhydrous or monohydrate?

Answer:It is anhydrous D-(+)-glucose, also called dextrose, with molecular formula C6H12O6.

Question: What is the supplied packaging quantity?

Answer:This variant contains 50 kg of glucose in a plastic drum, not the 5 kg bottle or 25 kg sack.

Question: Which pharmaceutical grade designations apply?

Answer:The EMPROVE EXPERT grade is designated Ph Eur, BP and USP and supports controlled pharmaceutical material qualification.

Application Note

Merck D-(+)-Glucose Anhydrous EMPROVE EXPERT is a pharmaceutical-grade dextrose ingredient supplied in a 50 kg plastic drum for formulation and manufacturing operations. The anhydrous monosaccharide has a molecular formula of C6H12O6, a molecular weight of 180.16 g/mol and CAS number 50-99-7. It carries Ph Eur, BP and USP grade designations, with analytical controls supporting material selection for regulated aqueous preparations. D-Glucose dissolves in water and provides a readily available carbohydrate source in defined formulations. In cell-processing or buffer-development workflows, its concentration influences solution osmolality and substrate availability; formulation suitability therefore depends on the complete system rather than glucose content alone. EMPROVE EXPERT documentation helps connect raw-material specifications to supplier qualification and change control. Bulk handling requires dry, closed storage and controlled dispensing to reduce moisture uptake and cross-contamination.

Ordering

Notice

Unless otherwise stated, the minimum order amount is USD 1,000.
For orders below USD 1,000, an additional handling fee may apply, or we may arrange local delivery / local handover where available.
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