Merck, 178462-50UG, Apolipoprotein C-II, Human Plasma, Very Low-Density Lipoprotein

General description
Native apolipoprotein C-II from human plasma. Found primarily in VLDL and chylomicrons. Functions as a cofactor for lipoprotein lipase. Elevated serum levels of Apo C-II are common in type I, III, IV, and V hyperlipoproteinemia. Low serum concentrations of Apo C-II are indicative of nephrotic syndrome (Tangier’s Disease).
Physical form
Lyophilized from 10 mM NH₄HCO₃, pH 7.4.
Preparation Note
Please refer to vial label for lot-specific volume prior to lyophilization.
Other Notes
Brunzell, J.D. 1989. in The Metabolic Basis of Inherited Disease,6th Edition (Scriver, G.R., ed.) p. 1165, McGraw Hill, New York.
Le, N.A., et al. 1988. J. Lipid Res. 29, 669.
Jackson, R.L., and Holdsworth, G. 1986. Methods Enzymol.128, Chapter 14.
Legal Information
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Disclaimer
Toxicity: Standard Handling (A)