Merck, 178468-50UG, Apolipoprotein E, Human Plasma, Very Low-Density Lipoprotein

General description
Native apolipoprotein E from human plasma. A component of VLDL and of a subclass of HDL. Present in normal plasma at concentrations of 50 µg/ml. Serves as a ligand for LDL receptors, where it participates in the transport and redistribution of cholesterol and other lipids. Also functions in immunoregulation and cell growth differentiation. Inhibits mitogen-induced T-lymphocyte proliferation and modulation of smooth muscle cell differentiation.
Packaging
Please refer to vial label for lot-specific concentration.
Physical form
In 50 mM NH₄HCO₃, pH 8.0.
Preparation Note
Following initial thaw, aliquot and freeze (-20°C).
Prepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
Other Notes
Kelly, M.E., et al. 1994. Cell Immunol. 159, 124.
Mahley, R.W. 1988. Science 240, 622.
Rall, S.C., et al. 1986. Methods Enzymol. 128, 273.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.
Toxicity: Standard Handling (A)