Description
General description
Red-Al® sodium bis(2-methoxyethoxy)aluminum hydride [NaAlH2(OCH2CH2OCH3)2] is used as a versatile reducing agent in organic synthesis. It is used to reduce:
Aldehydes, ketones, esters, and anhydrides to primary alcohols.
Ketoximes and aldoximes to primary amines.
Cyclic compounds such as lactones and epoxides to diols.
It is also used as a catalyst in the ring-opening polymerization reactions.
SBAH is a reducing agent used to reduce functional groups like carbonyls, amides, epoxides, esters, and carboxylic acids.
Application
Employed in the efficient reduction of N-Boc amino acid secondary amides leading to chiral diamines.
Red-Al® sodium bis(2-methoxyethoxy)aluminum hydride can be used as:
A tosyl deprotecting agent.
A catalyst for crosslinking of polyvinylsilanes (PVS) by Si-Si dehydrocoupling reaction in the presence of group 4 metallocene complexes.
A reducing reagent for the synthesis of optically active N-protected amino alcohols and peptide alcohols.
Legal Information
Red-Al is a registered trademark of Merck KGaA, Darmstadt, Germany