Description
General description
A potent inhibitor of protein phosphatase 2A (IC₅₀ = 50 nM).
Inhibits protein phosphatase 2A (IC₅₀ = 50 nM).
Biochem/physiol Actions
Cell permeable: no
Primary Target
PP2A
Product does not compete with ATP.
Reversible: no
Target IC₅₀: 50 nM against protein phosphatase 2A
Preparation Note
Following reconstitution, aliqot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Other Notes
Zhang, Z., et al. 1996. Biochemistry35, 1606.
Li, Y.-M., and Casida, J.E. 1992. Proc. Natl. Acad. Sci. USA89, 11867.
Graziano, M.J., et al. 1988. Mol. Pharmacol.33, 706.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)