Merck, 233490-500UG, Coagulation Factor XII, Human Plasma

General description
Coagulation Factor XII, Human Plasma, CAS 9001-30-3, is a native coagulation factor XI that once activated (principally by kallikrein), is converted to Factor α-XIIa.
Native coagulation factor XII from human plasma. A single-chain polypeptide, which once activated (principally from the action of kallikrein) is converted to Factor α-XIIa. Factor α-XIIa then converts Factor XI to Factor XIa.
Packaging
Please refer to vial label for lot-specific concentration.
Physical form
In 150 mM NaCl, 4 mM sodium acetate buffer, pH 5.3.
Preparation Note
Following initial thaw, aliquot and freeze (-70°C).
Prepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
Analysis Note
single band by SDS-PAGE
Other Notes
Specific activity is measured by clotting assay and compared to a standard curve produced using normal pooled human plasma.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)