Merck, 345876, Bovine γ-Globulin, Serum

General description
Native γ-globulin from bovine serum.
Native γ-globulin from bovine serum. Immunoglobulins (Igs) are glycoproteins found in serum and tissue fluids of all mammals. Some Igs act as cell surface receptors and others are antibodies that travel in the blood or lymph. Ig molecules have two functional regions, one which binds antigens and another which controls effector functions, such as binding to host cells. Structurally, Igs have two identical heavy polypeptide chains and two identical light polypeptide chains that are linked by disulfide bonds. The heavy chains determine an Ig′s class and subclass (isotype). Most higher mammals have five different classes of immunoglobulins: IgG, IgA, IgM, IgD, and IgE. CALBIOCHEM immunoglobulins are rigorously analyzed for purity and identity. Most are tested by using immunodiffusion, immunoelectrophoresis, and SDS-PAGE (the major precipitin pattern was observed in the γ region when assayed versus anti-whole bovine serum by IEP).
Preparation Note
Reconstitute in ≥0.2% NaCl.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)