Merck, 360481-4X4L, 1,4-Dioxane

General description
1,4-Dioxane is a heterocyclic organic compound that is commonly used as a solvent in several chemical reactions. It is also used as a stabilizer in chlorinated solvents.
Our premium ACS solvents are ideal for routine chemical synthesis, drying, purification, and critical labware cleaning. They meet or exceed the rigorous standards of the American Chemical Society (ACS), ensuring high-quality results for your research needs.

Premium ACS Solvents: Our solvents meet or exceed the stringent standards set by the American Chemical Society, ensuring high quality and reliability for your laboratory applications.

Replicable and Publishable Results: Designed for consistency, our solvents deliver results that can be reliably reproduced, making them ideal for research that requires publication.

Versatile Applications: Suitable for routine chemical synthesis, drying, purification, and critical labware cleaning, our solvents cater to a wide range of research needs in the laboratory.

Application
1,4-Dioxane can be used as:
A solvent in the N-methylation of amines by reductive functionalization of CO₂ in the presence of NaBH₄ as the reducing reagent.
An additive to synthesize 3-hydroxylisoindolin-1-ones via hydroxylhydrative aza-cyclization of 2-alkynylbenzamide.

A mixture of 1,4-dioxane/ethanol/formic acid solvent system can be used in the depolymerization of lignin to synthesize value-added phenolic monomers.