Merck, 407286-100UG, Anti-Integrin αv (Ab-1) Mouse mAb (272-17E6)

General description
Purified mouse monoclonal antibody. Recognizes the αv integrin chain and all αv-containing integrins.
Recognizes the αv integrin chain and all αv-containing integrins.
This Anti-Integrin αv (Ab-1) Mouse mAb (272-17E6) is validated for use in Cell Inhibition Assays, ELISA, FC, IP for the detection of Integrin αv (Ab-1).
Immunogen
Human
human placental αvβ₃ integrin
Application
Cell Inhibition Assays (see application reference)
ELISA (see application reference)
Flow Cytometry (2.5 µg/ml, see application reference)
Immunoprecipitation (2.5 µg/ml, see application reference)
Packaging
Please refer to vial label for lot-specific concentration.
Physical form
In PBS, pH 7.6.
Preparation Note
Following initial thaw, aliquot and freeze (-20°C).
Other Notes
Akiyama, S.K. 1996. Hum. Cell9, 181.
Hynes, R.O. 1992. Cell69, 11.
Albelda, S.M. and Buck, C.A. 1990. FASEB J.4, 2868.
Buck, C.A. and Horwitz, A.F. 1987. Ann. Rev. Cell Biol.3, 179.
Hynes, R.O. 1987. Cell45, 549.
Cross-reacts with all αv integrins. Blocks cell adhesion mediated by all αv integrins and in vivo melanoma growth and angiogenesis (see application references). Variables associated with assay conditions will dictate the proper working dilution.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)