Description
General description
A potent agonist and assumed endogenous ligand of GPR55, shown to induce rapid phosphorylation of p38 mitogen-activated protein kinase (MAPK) and its downstream activating transcription factor 2 (ATF2) in both GPR55-transfected HEK293 cells, and in IM-9 lymphoblastoid cells naturally expressing GPR55 at 1 µM, while having no effect on vector-transfected cells. In addition, shown to enhance serum induced cell migration in MCF-7 cells over expressing GPR55.
Packaging
Packaged under inert gas
Other Notes
Oka, S., et al. 2010. J Biochem.147, 671.
Oka, S., et al. 2007.
Biochem. Biophys. Res. Commun.362, 928.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)