Description
General description
Cell-permeable diacylglycerol analog that activates Ca²⁺-dependent protein kinase C. Also a stimulator of secretion and aggregation in blood platelets.
Note: 1 set = 10 x 500 µg.
Biochem/physiol Actions
Cell permeable: yes
Primary Target
Ca2+-dependent protein kinase C
Product does not compete with ATP.
Reversible: no
Preparation Note
Unstable in solution; reconstitute just prior to use. The material can be dissolved in chloroform, aliquoted, dried under a stream of nitrogen, and stored at -20°C.
Other Notes
Florin-Christensen, J. 1993. Biochem. J.289, 783.
Benz, I., et al. 1992. J. Membr. Biol. 130, 183.
Haeffner, E.W., and Wittmann, U. 1992. J. Lipid Mediat.5, 237.
Gilmore, T., and Martin, G.S. 1983. Nature306, 487.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)