Merck, 520659, Palladium(II) chloride

General description
Palladium(II) chloride (PdCl₂) reacts with unsubstituted or alkyl-substituted cyclic ketones in the CO atmosphere to afford acyclic diesters and acyclic chloro-substituted monoesters. PdCl₂ reacts with N,N-dimethylallylamine in methanol to afford di-μ-chloro-bis(2-methoxy-3-N,N-dimethylaminopropyl)dipalladium(II). Palladium dichloride, acetate and acetylacetonate in the [bmim][BF₄] or [bmim][PF₆] (where[bmim]⁺= 1-butyl-3-methylimidazolium cation) ionic liquids have been employed for the hydrodimerization of butadiene to form octa-2,7-dien-1-ol.

Palladium(II) chloride is used as an oxidizing agent and catalyst for the Suzuki-Miyaura and Mizoroki-Heck reactions.
Application
Palladium(II) chloride (PdCl₂) was used in the following studies:
As catalyst for the carbonylation of organic tellurides by reaction with carbon monoxide.
As a catalyst along with Cu(II) for the deamination of phenethylamines to phenyl substituted pyrroles.
Together with PEG 300, promoted efficient Suzuki-coupling of aryl chlorides with aryl boronic acids.
For small scale and high throughput uses, product is also available as ChemBeads (919853)
Application Guide for Palladium Catalyzed Cross-Coupling Reactions

Used in the synthesis of semiconducting metal-containing polymers in which the polypyrrole backbone has a conformational energy minimum and is nearly planar.