Merck, 650275, Trypsin, Iodination Grade, Human Pancreas

General description
Native trypsin from human pancreas. Serine protease that specifically hydrolyzes amides, peptides, and proteins at the C-terminus side of arginine and lysine residues.
Physical form
Salt-free.
Preparation Note
Following reconstitution, aliquot and freeze (-70°C).
Prepared from tissue that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
Other Notes
Merck Index13, 9865.
Travis, J., and Roberts, R.C. 1969. Biochemistry 8, 2884.
One unit is defined as the amount of enzyme that will hydrolyze 1 µmol of N-benzyl-L-arginine-pNA per min at 25°C, 200 mM Tris-HCl, pH 7.8, 20 mM CaCl₂.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Irritant (B)
when assayed against N-Suc-Ala-Ala-Pro-Phe-pNA (573462)