Merck, 700048P-1MG, 24(R/S),25-epoxycholesterol-d6

General description
24(R/S),25-epoxycholesterol-d6 is a deuterated side-chain substituted oxysterol.
Application
24(R/S),25-epoxycholesterol-d6 has been used as a primary and deuterated surrogate sterol standard in the quantitative analysis of extracted sterol samples from cultured cells and tissues.
Biochem/physiol Actions
Deuterated sterol plays a vital role in chemical and biochemical research. It is used as a mechanistic tracer to study the role of steroid hormones in the function and modulation of several physiological processes. Deuterated sterol is also used as reference standards for mass spectrometry. 24(R/S),25-epoxycholesterol-d6 is a deuterium labeled sterol.
24(S),25-epoxycholesterol maintains cholesterol homeostasis. It modulates hepatic cholesterol metabolism in vivo. 24(S),25-epoxycholesterol is synthesized in the mevalonate pathway. It inhibits sterol regulatory element-binding protein (SREBP) activation.
Packaging
5 mL Amber Glass Screw Cap Vial (700048P-1mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC