Merck, 810131C-1MG, 16:0-12:0 NBD PC

General description
Phosphatidylcholine (PC) is a common phospholipid found in eukaryotes and a prime metabolite of glycerolipid metabolism. It is a vital component of the mucosal layer of the colon. NBD PC is a fluorescently labeled lipid with 7-nitrobenz-2-oxa-1,3-diazol-4-yl (NBD) attached to phosphatidylcholine.
Application
16:0-12:0 NBD PC has been used as a fluorescent marker to study the adsorption of hyaluronan (HA) onto a 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC) bilayer deposited on a silica surface by fluorescent microscopy. It may also be used:
in the microfluidic chip-based technology to demonstrate separation of fluorophore-labeled phospholipids and to monitor enzyme activities of lipid-modifying enzymes
as a fluorophore for DPPC in fluorescence recovery experiments
as a substrate to test scramblase activity

Biochem/physiol Actions
7-nitrobenz-2-oxa-1,3-diazol-4-yl phosphatidylcholine (NBD PC) is useful in the study of cellular processes as it functions as a fluorescent analog in lipid membranes and phospholipid phase transitions.
Packaging
5 mL Amber Glass Screw Cap Vial (810131C-1mg)
5 mL Amber Glass Screw Cap Vial (810131C-5mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC