Merck, 850697P-25MG, 06:0 PE

General description
06:0 Phosphatidylethanolamine (PE) is a water-soluble short-chain glycero-phospholipid. It is primarily found in the inner leaflet of the plasma membrane.
Phosphatidylethanolamine (PE), an abundant phospholipid in the inner mitochondrial membrane accounts for 15–25% of the total lipid in the cells of mammals.
Application
06:0 Phosphatidylethanolamine (PE) has been used as a ligand in the co-crystallization of broadly neutralizing anti-HIV antibody 4E10. It has also been used as one of the phospholipids (PLs) standards for the analysis of bovine milk PL classes by normal-phase high-performance liquid chromatography (NP-HPLC).
06:0 PE (1,2-dihexanoyl-sn-glycero-3-phosphoethanolamine/DHPE) may be used:
as a substrate for glycerophosphoethanolamine ethanolaminephosphodiesterase (GPE-EP) in specificity assay
as a phosphoethanolamine (PE) standard in liquid chromatographic analysis of milk phospholipids
as a phospholipid substrate to study the kinetic parameters for the glucose transporter type 4 (Glu4) mutants

Biochem/physiol Actions
06:0 Phosphatidylethanolamine (PE) plays an important role in various cellular processes such as autophagy, cell division and protein folding. In addition it also acts as a precursor for the synthesis of several protein modifications and as an intermediate in the synthesis of other glycerophospholipids.
Phosphoethanolamine (PE) serves as a precursor in membrane phospholipid biosynthesis. Phosphatidylethanolamine controls membrane fluidity in eukaryotic cells.
Packaging
5 mL Clear Glass Sealed Ampule (850697P-25mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC