Merck, 938831-1KT, NanoFabTx™ Polymers for Microneedles

Application
NanoFabTx™ Polymers for Microneedles are carefully selected polymers that can be used to formulate microneedle patches. Microneedles are tiny projections of polymeric needles that can vary in length, pitch, and array for topical drug delivery applications. They are typically composed of biodegradable synthetic or natural polymers at a variety of suitable concentrations.
Gelatin methacrylate (GelMA) is one of the most common natural polymers used in a variety of biomedical applications due to its suitable biological properties and tunable physical characteristics. GelMA can be used to form hydrogels via photopolymerization with photoiniatiors such as lithium phenyl-2,4,6-trimethylbenzoylphosphinate (LAP). GelMA hydrogel microneedles have been used to encapsulate and delivery a variety of therapeutics including small molecules, exosomes, and proteins.
Features and Benefits
The NanoFabTx™ Polymers for Microneedles can be used with microneedle templates to formulate microneedles for drug delivery applications. The selected polymer will enable users to:

1)save time in selecting the polymer and provide a starting point to formulate microneedles by avoiding lengthy trial-and-error optimization.
2)formulate microneedles for various drug delivery applications.
Preparation Note
For more information on the protocols, please refer to Product Information under the document section of this page.
Legal Information
NANOFABTX is a trademark of Sigma-Aldrich Co. LLC