Merck, 9495-4L, Polysorbate 80

General description
Non-ionic detergent suited for solubilization of membrane proteins, enzymology, analytical, and diagnostic, work as well as chromatography and electrophoresis. Molecular Biology Grade.

DNAse: none detected
Heavy metals (as Pb): ≤0.001%
Hydroxyl number: 65-80
Residue after ignition: ≤0.25%
Moisture (H2O): ≤3%
Protease: none detected
RNAse: none detected

Intended for laboratory and manufacturing use only. Not for drug, food, or household use.
Application

Surfactants′ Interplay with Biofilm Development in Staphylococcus and Candida.: This study explores how surfactants, including Polysorbate 80, influence biofilm development in Staphylococcus and Candida species. The findings highlight the critical role of surfactants in modulating biofilm formation, which has implications for developing new therapeutic strategies against biofilm-associated infections. (Aonofriesei, 2024).

Stress-mediated polysorbate 20 degradation and its potential impact on therapeutic proteins.: This article examines the degradation of Polysorbate 20 under stress conditions and its effects on therapeutic proteins. While primarily focusing on Polysorbate 20, the insights are relevant for understanding the stability and formulation challenges of similar surfactants like Polysorbate 80 in pharmaceutical applications. (Aryal et al., 2024).

Dissecting the toxicological profile of polysorbate 80 (PS80): comparative analysis of constituent variability and biological impact using a zebrafish model.: This comprehensive study evaluates the toxicological effects of Polysorbate 80 using a zebrafish model, providing detailed insights into its safety profile and biological impact, which are crucial for its use in pharmaceuticals and other applications. (Wang et al., 2024).

Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
OMNIPUR is a registered trademark of Merck KGaA, Darmstadt, Germany
TWEEN is a registered trademark of Croda International PLC
Disclaimer
Toxicity: Irritant (B)