Merck, CLS356230-1EA, Corning®Matrigel®Growth Factor Reduced (GFR) Basement Membrane Matrix

General description
Corning Matrigel Growth Factor Reduced (GFR) Basement Membrane Matrix, 5 mL, is suited for applications requiring a highly defined basement membrane preparation. Available in standard GFR, High Concentration (HC), and Phenol Red-free formats. Corning Matrigel matrix is a solubilized basement membrane preparation extracted from the Engelbreth-Holm-Swarm (EHS) mouse sarcoma, a tumor rich in extracellular matrix proteins, including Laminin (a major component), Collagen IV, heparan sulfate proteoglycans, entactin/nidogen, and a number of growth factors.

Quality

Mouse colonies routinely screened for pathogens via Mouse Antibody Production (MAP) testing
Extensive PCR testing is performed to screen for a number of pathogensTested and found negative for bacteria, fungi, and mycoplasma
Protein concentrations determined by Lowry method
Endotoxin units measured by Limulus Amoebocyte Lysate assay
Matrigel Matrix gel stability is tested for a period of 14 days at 37°C
Biological activity is determined for each lot using a neurite outgrowth assay.
Source
EHS mouse tumor

Application

Cell Growth and Differentiation
Metabolism/Toxicology Studies
Invasion Assays
in vitro and in vivo Angiogenesis Assays
in vivo Angiogenesis Studies and Augmentation of Tumors in Immunosuppressed Mice
Preparation and Storage
Store at -20°C. Avoid multiple freeze-thaws.

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For Customers in California only: WARNING Please refer to Safety Data Sheet (SDS) Section 15 or Letter in Lieu for more information regarding California Proposition 65.
Legal Information
Corning is a registered trademark of Corning, Inc.
Matrigel is a registered trademark of Corning, Inc.