Merck, CPG-504-2ML, Anionic Liposomes

General description
Liposomes are extensively used to study the interaction of proteins, peptides and other molecules with the surface of a lipid membrane. One of the parameters that affects this interaction is the charge of the liposomal membrane. Phosphatidylglycerol (PG) is a negatviely charged molecule. The amount of the negative zeta potential in the liposomes depends on the molar percentage of PG in the formulation. The anionic-phosphatidylglycerol (PG) liposome catalog contains products made from 0.5 up to 100 percent DOPG with various amount of negative zeta potentials. The matrix lipid DOPC used in the formulation does not significantly contribute to the charge of the liposomes.
Application
Drug delivery
Lipid-protein interactions

Preparation Note
Liposomes should never be frozen. Liposomes should be stored in the dark at 4°C, except when brought to room temperature for brief periods prior to use.

Liposomes are made under sterile conditions. If you need to take multiple aliquots out of the vial, it is advised to take extreme care in not contaminating the vial. It is recommended to handle the vial under a sterile hood to maintain the sterility of the product. Liposomes should never be frozen. Ice crystals that form during freezing will rupture the lipid membrane of the liposomes and change the size of liposomes particles.
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Disclaimer
For research use only