Merck, D1556-250ML, OptiPrep™ Density Gradient Medium

General description
OptiPrep™ Density Gradient Medium, also known as iodixanol, is a low osmolarity, non-ionic iodinated density gradient medium. It is a sterile and endotoxin-tested solution that comprises 60% (w/v) iodixanol in water, designed for the in vitro isolation of biological particles. It may be used for fractionation and separation of cell and subcellular organelles.
Application
OptiPrep™ has been used to isolate molecules, cells, and subcellular organelles, including DNA, cytokines, lysosomes, endoplasmic reticulum, peroxisomes, T lymphocytes, and natural killer cells. It has also been used for the following applications:

to investigate the efficiency of single-cell encapsulation.
the gradient-based isolation of senescent cancer cells.
isolation of non-enveloped virion isolation from bronchoalveolar lavage.
isolation of lipoproteins and macromolecules
purification of virions
purification of neuron cells

Features and Benefits
OptiPrep™ has numerous biocompatible properties that make it ideal for use.
It is biologically inert and does not interfere with assays for marker enzymes.
It is non-ionic, non-toxic, and has low osmotic pressure.
It forms spontaneous gradients that are stabler and easier to prepare than sucrose.

Other Notes
60% (w/v) solution of iodixanol in water (sterile).
Legal Information
OptiPrep is a trademark of Serumwerk Bernburg AG