Merck, GE17-5073-01, SP Sepharose™XL

General description
SP Sepharose™ XL is a strong cation exchanger designed for use in the capture steps of biomolecules from clarified feed-stocks.
Application
SP Sepharose™ XL is based on a highly cross-linked, bead formed 6% Agarose matrix similar to the well established SP Sepharose™ Fast FLow media. Dextran chains are covalently coupled to the Agarose matrix and modified with sulphopropyl (SP) strong cation exchange groups through chemically stable ether bonds. The stable Agarose matrix and long, flexible chains of Dextran with bound charged groups work together to increase loading capacity whilst allowing high flow rates

With its high loading capacities and excellent physical and chemical stability, SP Sepharose™ XL is suitable for the capture stage of a downstream process, which is characterised by large loads of crude samples.

As member of the BioProcess media range, SP Sepharose™ XL meets industrial demands with security of supply and comprehensive technical and regulatory support.
Features and Benefits
High loading capacities give more productive capture from clarified feedstocks.
Strong cation exchanger designed for capture steps
High chemical stability for effective CIP/sanitization
The hydrophilic nature of the base matrix ensures Low levels of non-specific binding leading to Low levels of host cell-derived impurities in the elution pool.

Preparation Note
Please be aware this product may be shipped 90 days before the expiration date. For more information on the batch specific expiration date, please contact technical service.
Store at 4 to 30 °C (20% Ethanol + 0.2 M Sodium Acetate)
Analysis Note
To view the Certificate of Analysis for this product, please visit www.cytiva.com.
Legal Information
Sepharose is a trademark of Cytiva