Merck, H2667-100UG, Histone H4 human

General description
Histones are highly basic chromatin proteins. They tightly pack and organize eukaryotic DNA into nucleosomes. Nucleosomes consist of a histone octamer made of a tetramer of histones H3 and H4 with two dimers of histones H2A and H2B, wherein the 147 DNA base pairs are wrapped around this histone complex.
Application
Histone H4 human has been used in far-western blot analysis for protein identification. It has also been used in the preparation of standard protein solution for protein digestion.
Biochem/physiol Actions
Histones regulate transcription, DNA replication, DNA repair, and recombination.
Other Notes
Supplied as 1 mg/mL in 20 mM NaPO₄, pH 7.0, 0.3 M NaCl, 1 mM EDTA