Description
General description
Circulating cancer biomarkers give insight beyond intracellular oncogenesis and into how the body responds to the presence of a tumor, the dysregulation of homeostasis, and the relationship between a tumor and its environment. Multianalyte panels have become essential tools that enable researchers to measure cancer biomarkers simultaneously, teasing out these relationships and applying them to understand tumor biology.
Application
MILLIPLEX® Qualified assays undergo rigorous assay development, verification, and Quality Control testing to achieve optimal performance. Simultaneously analyze up to 10 analytes in human serum, plasma, and cell culture supernatants.
Analytes included: Aldheyde dehydrogenase 1 Family, Member A1 (ALDH1A1), Carbonic Anhydrase IX (CA9), CD44, Epithelial cell adhesion molecule (EpCAM), Hepsin, Kallikrein-6, Mesothelin, Midkine, Neural cell adhesion Molecule L1 (L1CAM), Transglutaminase 2 (TGM2)
Assay Characteristics: Refer to kit protocol for assay cross-reactivity, sensitivity, precision, and accuracy.
Features and Benefits
Versatile 10-Plex Analyte Kit: This panel allows for the simultaneous quantification of ten significant biomarkers, including ALDH1A1, CA9, and CD44, providing a broad scope for cancer research.
Diverse Sample Compatibility: Suitable for human serum, plasma, and tissue culture supernatants, allowing flexibility in sample types for various research applications.
Recommended Sample Dilution: The assay suggests using 25 μL of 1:5 diluted serum or plasma, with tissue culture supernatants requiring appropriate dilution, simplifying the preparation process.
Comprehensive Insights into Tumor Dynamics: By enabling the simultaneous measurement of multiple circulating biomarkers, this panel aids researchers in exploring the complex interactions between tumors and their microenvironment.
Increased Efficiency in Research: The multiplex capability allows for a significant boost in sample throughput, enabling researchers to analyze a larger number of samples in less time, which is crucial for high-volume research.
Legal Information
Luminex is a registered trademark of Luminex Corporation
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp
Disclaimer
For research use only. Not for use in diagnostic procedures.
Label License/Sticker for Assay Product:
By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.
