General descriptionThe HER2 Analyte ControlDR has four cell line cores which demonstrate a full range of expression for HER2. The cell lines selected incorporate HER2 expression levels of 0, 1+ (both non-amplified), 2+ (equivocal), and 3+ (amplified).
HistoCyte Laboratories control slides and blocks are made from cultured human cell lines to provide the required range of expression of a specific biomarker. The cell lines are processed using proprietary methods that allow for the creation of a high density embedded cell block with cores that retain their cellular morphology. Available as pre-cut unstained slides or as cell microarray blocks for sectioning.
ApplicationIdeal for use as a same slide control for immunohistochemistry (IHC) and in situ hybridization (ISH). This control has been developed for researchers who require a reliable, sensitive and accurate control for HER2.
The HER2 Analyte ControlDR histology slides have four cell line cores providing a dynamic range of expression of HER2. Analyte controls are placed at one end of slide, allowing sample application on same slide for valid comparison.
The HER2 Analyte ControlDR cell microarray block contains four cell line cores that are 2 mm in diameter and between 3.0-3.5 mm in length. The cell microarray block may yield over 300 sections depending on thickness.
Preparation NoteCell microarray blocks are fixed in 10% neutral buffered formalin and embedded in paraffin wax. Pre-cut unstained slides are prepared from 4 μm thick sections, mounted on positively charged slides, and dried at 37 °C overnight.
Other NotesFor certificates of analysis, contact
[email protected].
HER2 Analyte ControlDR brochure is available from HistoCyte Laboratories.
