General description
The MILLIPLEX® PLEXpedition Screening Panel is a configurable multiplex immunoassay kit designed to simultaneously screen up to 115 targets, including cytokines, chemokines, and biomarkers related to bone health, metabolism, and cardiovascular disease. This discovery biomarker tool is offered in a matrix-free format for analyte detection across various sample types and serves as a bridge to to our commercially available Qualified assays for later-stage drug development and biomarker analysis.
Application
FLEXMAP 3D®/xMAP® INTELLIFLEX required for any or all of the following 115 analytes: ACTH, Amylin (Active), BCA-1, BDNF, BNP, CK-MB, C-Peptide, DKK1, EGF, ENA-78, Eotaxin, Eotaxin-2, Eotaxin-3, Erythropoietin (EPO), FABP3, FABP4, FGF-2, FGF-21, FGF-23, FLT3 Ligand, Fractalkine, G-CSF, Ghrelin (Active), GIP, GLP-1 Total, Glucagon, GM-CSF, GPC-2, Granzyme A, Granzyme B, GROα, HB-EGF, HGF, I-309, IFNα2, IFNγ, IL-1α, IL-1β, IL-1Ra, IL-2, IL-3, IL-4, IL-5, IL-6, IL-7, IL-8, IL-9, IL-10, IL-11, IL-12 (p40), IL-12 (p70), IL-13, IL-15, IL-17A, IL-17F, IL-18, IL-21, IL-22, IL-23, IL-33, Insulin, IP-10, I-TAC, Leptin, LIF, MCP-1, MCP-2, MCP-3, MCP-4, M-CSF, MDC, MIG, MIP-1α, MIP-1β, MIP-1Ϭ, MIP-3α, MIP-3β, MMP-1, MMP-10, MMP-12, MMP-2, MMP-3, MMP-7, MMP-9, Myostatin, NGF, NTproBNP, OPG, OPN, Osteocalcin, Osteonectin, PDGF-AA, PDGF-BB, Perforin, PlGF, PP, PYY, RANTES, sCD40L, SCF, SDF-1, sFAS, sFASL, SOST, TARC, TGFα, TNFα, TNFβ, TPO, TRAIL, Troponin I, TSLP, VEGF-A, VEGF-C, VEGF-D.
Assay Characteristics: Refer to kit protocol for assay cross-reactivity and precision.
MILLIPLEX® Screening assays are fit-for-purpose tools to enable the detection of biomarkers spanning mutiple research areas during discovery and translational studies. Simultaneously analyze up to 115 analytes in mutiple human sample types including serum, plasma,cerebrospinal fluid (CSF), cell culture supernatants, brochoalveolar lavage (BAL), and milk.
Analytes included: The Luminex® xMAP® INTELLIFLEX and the FLEXMAP 3D® can detect all 115 analytes in this panel while the MAGPIX® and Luminex 200™ instruments detect specific subsets of 50 and 80 analytes, respectively.
MAGPIX®/Luminex 200™/FLEXMAP 3D®/xMAP® INTELLIFLEX required for any or all of the following 50 analytes: EGF, FGF-2, Fractalkine, G-CSF, Ghrelin (Active), GIP, Glucagon, GM-CSF, Granzyme B, GROα, HGF, IFNα2, IFNγ, IL-1α, IL-1β, IL-1Ra, IL-2, IL-4, IL-5, IL-6, IL-7, IL-8, IL-10, IL-12 (p40), IL-12 (p70), IL-13, IL-15, IL-17A, IL-18, IL-22, IL-23, IP-10, Leptin, MCP-1, MIG, MIP-1α, MIP-1β, OPN, PDGF-AA, PDGF-BB, Perforin, RANTES, sCD40L, SCF, sFAS, sFASL, TGFα, TNFα, TRAIL, VEGF-A.
Luminex 200™/FLEXMAP 3D®/xMAP® INTELLIFLEX required for any or all of the following 80 analytes: ACTH, BDNF, C-Peptide, EGF, Eotaxin, FABP4, FGF-2, FLT3 Ligand, Fractalkine, G-CSF, Ghrelin (Active), GIP, GLP-1 Total, Glucagon, GM-CSF, Granzyme A, Granzyme B, GROα, HGF, IFNα2, IFNγ, IL-1α, IL-1β, IL-1Ra, IL-2, IL-3, IL-4, IL-5, IL-6, IL-7, IL-8, IL-9, IL-10, IL-12 (p40), IL-12 (p70), IL-13, IL-15, IL-17A, IL-17F, IL-18, IL-21, IL-22, IL-23, IL-33, Insulin, IP-10, I-TAC, Leptin, MCP-1, MCP-3, M-CSF, MDC, MIG, MIP-1α, MIP-1β, MIP-3α, MMP-1, MMP-2, MMP-7, MMP-9, OPG, OPN, PDGF-AA, PDGF-BB, Perforin, PlGF, PP, PYY, RANTES, sCD40L, SCF, sFAS, sFASL, TARC, TGFα, TNFα, TNFβ, TRAIL, Troponin I, VEGF-A.
Features and Benefits
115-Plex Capability: Screen up to 115 biomarkers simultaneously, streamlining your research and maximizing data output in a single assay run.
Sample Agnostic Design: Flexibility to analyze a wide variety of sample types, enhancing the applicability of your research across different biological contexts.
Belysa Software Integration: Utilize advanced curve fitting software to ensure reliable data analysis with every run.
Easy Transition to Qualified Assays: Seamlessly move from screening to qualified quantification with kits that share critical raw materials.
Comprehensive Analyte Coverage: Benefit from a broad selection of biomarkers relevant to inflammation, metabolism, cardiovascular health, and more.
Robust Technical Support: Access dedicated expert sales specialists and application scientists to assist with your biomarker needs.
Legal Information
Luminex is a registered trademark of Luminex Corporation
FLEXMAP 3D is a registered trademark of Luminex Corp
Luminex 200 is a trademark of Luminex Corp
MAGPIX is a registered trademark of Luminex Corp
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp
Disclaimer
For research use only. Not for use in diagnostic procedures.
Label License/Sticker for Assay Product:
By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.
