Merck, HT501640-19L, Formalin solution, neutral buffered, 10%

Name: Formalin solution, neutral buffered, 10%
Brand: Merck
SKU: HT501640-19L

Size:19 L, 10% NBF, 10% Neutral Buffered Formalin, Formaldehyde, Methanal, histological tissue fixative

Catalog Number: HT501640-19L

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Category

General Purpose Solvents

Pack Size19 L

TagsClinical & Diagnostics Tissue Diagnostics Hematology Stains

CollectionsMerck Tissue Diagnostics – Universal Reagents for Histology & IHC Merck Cell Culture Supplements & Reagents: Complete Solutions for Research & Bioproduction Merck Roche Life Science Products for PCR, RT‑PCR & Nucleic Acid Purification

Description

General description
10% Neutral Buffered Formalin is the most used fixative throughout the world for light microscopy. Formalin solution is the commercially obtained solution containing 37% w/w (40% w/v) of formaldehyde in water. It requires a relatively short period of fixation. It is suitable for the long-term storage of tissue. Once properly fixed, the tissue should be able to withstand the subsequent stages of tissue processing or staining.
Application
Formalin solution (neutral buffered, 10%) has been popularly used as a general-purpose histological fixative to fix tissue samples.

It helps to preserve tissue samples by preventing decay and maintaining their molecular integrity.
It effectively preserves the cellular and tissue morphology, maintaining the structural integrity required for microscopic examination.
It is used for routine histological staining, providing clear and detailed images of cellular structures.

Popular general purpose histological fixative.
Biochem/physiol Actions
Formaldehyde is both a non-coagulant and an additive fixative. Formalin fixation is thought to form cross links between the aldehydes and the proteins, creating a gel, thus retaining cellular constituents in their in vivo relationship. Formaldehyde is known to penetrate tissue quickly, but the fixation process may take a long time to form the various cross links with tissue proteins.
Features and Benefits

10% NBF is well-suited for large throughput laboratories.
It requires a relatively short period of fixation.
It can be used for the long-term storage of tissue.

Packaging
Item is packaged in a 20 L Cubitainer consisting of a plastic bladder inside of a cardboard box with an attached spigot.
Physical form
Neutral buffered solution

Specifications

General

UNSPSC Code	12352114
PubChem Substance ID	24895891
NACRES	NA.47
MDL number	MFCD00003274
SMILES string	[O-]#[C+H2]
InChI	1S/CH2O/c1-2/h1H2
InChI key	WSFSSNUMVMOOMR-UHFFFAOYSA-N
concentration	10% formalin (approx. 4% formaldehyde)
color	colorless
pH	6.90-7.10
density	1.080 g/cm3
application(s)	hematologyhistology
storage temp.	room temp
Quality Level	200

Ordering

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Merck, HT501640-19L, Formalin solution, neutral buffered, 10%

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General

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