Merck, L050083-200L, Cap B

General description
Cap B solution contains tetrahydrofuran (THF), pyridine, and N-methylimidazole (NMI). It is mixed in situ with Cap A solution during the capping (acetylation) reaction. Pyridine is applied as a mild base while NMI provides a powerful acylation catalyst.
Packaging
200L stainless steel returnable drum
Preparation Note
Tetrahydrofurane / N-Methylimidazole / Pyridine 8/1/1 (v/v/v)
Other Notes
Cap B solution, containing tetrahydrofuran (THF), pyridine and N-methylimidazole (NMI), is mixed in situ with Cap A solution during the capping (acetylation) reaction. Pyridine is applied as a mild base while NMI provides a powerful acylation catalyst.