Merck, L0636-5MG, Lectin from Triticum vulgaris (wheat)

General description
Lectin from Triticum vulgaris (wheat) is a dimeric glycoprotein of 36 kDa. It belongs to the family of chitin-binding proteins. Glycosylated precursor of lectin is synthesized in endoplasmic reticulum.
Application
Lectin from Triticum vulgaris (wheat) has been used:
to conjugate with N-hydroxysuccinimide (NHS) dye
to inhibit nuclear import
to inhibit the nuclear pore of human cervical carcinoma HeLa and SiHa cells

Biochem/physiol Actions
Lectin from Triticum vulgaris (wheat) possessing four binding sites is specific for N-acetyl-d-glucosamine and N-acetyl-d-neuraminic acid (sialic acid) residues. Lectins also function as a fungicide. They also possess anti-nutritive effects.
WGA is not blood group specific but has an affinity for N-acetyl-β-D-glucosaminyl residues and N-acetyl-β-D-glucosamine oligomers. WGA contains no protein-bound carbohydrate.
Preparation Note
Conjugates are prepared from affinity purified lectin.
Other Notes
Highly purified