Description
General description
Mupirocin is produced by Pseudomonas fluorescens. Mupirocin is used to treat impetigo and skin infections.
Application
Mupirocin has been used:
for kinetic assay
to assess its resistance by performing turbidity assay
to determine its antimicrobial susceptibility
Biochem/physiol Actions
Antibiotic; inhibits isoleucyl-tRNA synthetase (IRS).
Features and Benefits
This compound was developed by GlaxoSmithKline. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
Preparation Note
Mupirocin is poorly soluble in water (26 mg/L), but highly soluble in DMSO (≥10 mg/mL). If sterilization is required, it is advisable to use filter sterilization with a 0.22 µm PTFE, Polypropylene, or Nylon filter membrane.