Merck, MABC1731-100UL, Anti-B7-H3 (CD276) Antibody, clone 376.96

General description
57.23 kDa calculated.
Cultured COLO 38 human melanoma cells.
Application
Epitope: extracellular domain
Biochem/physiol Actions
Clone 376.96 is a mouse monoclonal antibody that specifically detects human B7-H3 (CD276). It targets an epitope within the extracellular domain.

Physical form
Purified mouse monoclonal antibody IgG2a in PBS without azide.

Preparation Note
Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Analysis Note
Evaluated by Flow Cytometry in SK-OV-3 cells.

Flow Cytometry Analysis: 1 µg of this antibody detected B7-H3 (CD276) in one million SK-OV-3 cells.

Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.