Merck, MABC550, Anti-Pex3 Antibody, clone 14F3.2

General description
Pex3 (also known as peroxin-3, peroxisomal assembly protein PEX3, peroxisomal biogenesis factor 3, transformation-related protein 18) is a multitransmembrane peroxisome protein that is encoded by the PEX3 gene in human (also known as PBD10A and TRG18). Pex19 is involved in maintaining peroxisome biosynthesis and integrity by acting as a docking factor for pex19 and, together with other peroxins (PEXs), is essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs), including Zellweger syndrome (ZWS), neonatal adrenoleukodystrophy (NALD), infantile Refsum disease (IRD), and classical rhizomelic chondrodysplasia punctata (RCDP), are lethal diseases characterized by multiple defects in peroxisome function, resulting in failure of importing one or more classes of peroxisomal matrix proteins into the organelle.
Immunogen
GST-tagged recombinant protein corresponding to human Pex3.
Application
Anti-Pex3 Antibody, clone 14F3.2 is an antibody against Pex3 for use in Western Blotting and Immunohistochemistry.
Immunohistochemistry Analysis: A 1:50-1,000 dilution from a representative lot detected Pex3 in human liver and human kidney tissue.
Analysis Note
Evaluated by Western Blotting in HepG2 cell lysate.

Western Blotting Analysis: 0.5 ug/mL of this antibody detected Pex3 in 10 ug of HepG2 cell lysate.
Other Notes
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial