Merck, MABF287, Anti-FPR1, C-Term Dephospho Antibody, clone NFPRb

General description
40 kDa calculated
His-tagged recombinant protein corresponding to human FPR1 near the C-terminus.
Application
Epitope: Near C-terminus
Biochem/physiol Actions
Clone NFPRb selectively detects FPR1 with non-phosphorylated C-terminal tail. Diminished immunoreactivity is an indication of enhanced FPR1 C-terminal tail phosphorylation or neutrophils activation. Clone NFPRb is not reactive toward N-formyl peptide receptor 2 (encoded by FPR2/FPRL1 gene) regardless of its phosphorylation state (PMID 16675446, 17675514, 23873933).
Physical form
Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Preparation Note
Stable for 1 year at 2-8°C from date of receipt.
Analysis Note
Evaluated by Flow Cytometry in human peripheral blood mononuclear.

Flow Cytometry Analysis: 1.5 µg of this antibody detected FPR1 in human peripheral blood mononuclear.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.