Merck, MABS444, Anti-CLCA1 Antibody, clone 4D2.2

General description
GST-tagged recombinant protein corresponding to an internal fragment from the C-terminal half of human CLCA1.
~83 kDa observed. 125 kDa glycosylated precursor form, 90 kDa and 37-41 kDa processed/cleaved fragements reported (Gruber, A.D., et al. (1998). Genomics. 54(2):200-214).
Application
Epitope: Internal (C-terminal half).
Biochem/physiol Actions
Detects the 90 kDa processed/cleaved 4-transmembrane glycoprotein, but not the cleaved 37-41 kDa C-terminal fragment.
Physical form
Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Preparation Note
Stable for 1 year at 2-8°C from date of receipt.
Analysis Note
Evaluated by Western Blotting in human small intestine tissue lysate.

Western Blotting Analysis: 0.5 µg/mL of this antibody detected CLCA1 in 10 µg of human small intestine tissue lysate.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.