Merck, MABS676, Anti-KLF15, clone 2G8 Antibody

General description
KLF15 (Kruppel-like factor 15), also known as KKLF, DKFZp779M1320. Entrez Protein NP_054798. Sequence analysis predicted that the 416 amino acid KLF15 protein, which is 84% identical to the rat Klf15 protein, contains 3 zinc finger motifs at its C terminus, N-terminal serine-rich stretches, and a central proline-rich segment.KLF15, a kidney-enriched Krueppel-like factor, is a transcriptonal activator that binds the CLCNKA promoter. KLF15, which is a nuclear protein, is expressed primarily in liver, heart, skeletal muscle and kidney tissues but is not detected in lymphoid tissues or bone marrow. KLF15 is an important regulator of GLUT4 in both adipose and muscle tissues.
Immunogen
Purified recombinant fragment of human KLF15 expressed in E. Coli.
Analysis Note
Evaluated by Western Blotting in HepG2 and SMMC-7721 cell lysates.

Western Blotting Analysis (WB): A 1:500-2,000 dilution of this antibody detected KLF15 in HepG2 and SMMC-7721 cell lysates.
Other Notes
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