Merck, MAK634-1KT, Parallel Artificial Membrane Permeability Assay Kit

General description
Membrane permeability is an important characteristic for evaluating compounds as potential drug candidates. Drugs often need to cross cell membranes in order to reach their target of action and this makes a compound’s ability to passively cross these membranes an important characteristic to evaluate. Permeability can be evaluated by cell-based methods; however, these methods are often expensive and time consuming. Parallel Artificial Permeability Assays (PAMPA) offer researchers a quick, inexpensive method of evaluating the permeability of test compounds.

The PAMPA Kit provides all the necessary components to run a Parallel Artificial Permeability Assay for gastrointenstinal (GI) membrane permeability.
Application
Suitable for the quantitative determination of gastrointestinal (GI) membrane permeability of test compounds.