Merck, MBD0009-1ML, Inactivated Porphyromonas gingivalis

General description
Standardization of sample analysis is currently needed in microbiome genomics research workflow. Lack of standardization can lead to biases and errors in common processes during sample preparation and analysis such as sample amplification, sequencing and bioinformatics analyses. Inactivated Prophyromonas gingivalis can serve as standard for benchmarking the performance along the workflow of microbiomics or meta-genomics analyses and as a tool to increase reproducibility and allow comparison of results obtained by different labs. Porphyromonas gingivalis, is a gram negative bacterium which is an etiologic agent of adult periodontitis, a chronic inflammatory disease characterized by the destruction of the supportive tissue surrounding teeth. Studies have shown that LPS from P. gingivalis plays an important role in this disease. The association of the oral microbiota, including P. gingivalis, with various pathological states has been reported. These include development of Alzheimer’s disease, role in oral cancers, preterm birth and rheumatoid arthritis.

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Application
Inactivated bacteria are provided at >10^8 bacteria/vial as lyophilized powder. It is recommended to avoid freeze thaw cycles of this product.
Physical form
Powder -The inactivated bacteria are provided at >10^8 bacteria/vial as lyophilized powder