| UNSPSC Code | 23151806 |
|---|---|
| Web Name Suffix Override | C0HC, filtration area 1.1 m², Process Scale |
| eCl@ss | 32031690 |
| material | cellulose |
| description | Perfusion bioreactor fluid |
| feature | hydrophilic |
| manufacturer/tradename | Millistak+® |
| parameter | 1 bar max. differential pressure (15 psid) at 80 °C (Forward) |
| H | 32 cm (12.5 in.) |
| L | 62 cm (24.2 in.) |
| filtration area | 1.1 m2 |
| impurities | <0.25 EU/mL bacterial endotoxins (LAL test, Aqueous extraction) |
| gravimetric extractables | 39-69 mg/m2 |
| total organic carbon (TOC) residue | 720-1260 ppb |
| input | sample type liquid |
| conductivity | 8.66-10.5 μS/cm at 25 °C (product water) |
| filter grade | C0HC |
| Quality Level | 400 |
Answer:The C0HC medium contains cellulose and inorganic filter aid, with glass-fiber-reinforced polypropylene structural components.
Answer:MC0HC10FS1 provides 1.1 m² of filtration area.
Answer:Yes. It supports one autoclave cycle of 60 minutes at 123 °C.
Millistak+® HC Pod Depth Filter MC0HC10FS1 is used for primary clarification of perfusion-bioreactor fluid and for primary or secondary clarification of cell cultures, yeast and E. coli lysates after centrifugation, E. coli refolds, media, vaccines, plasma proteins, and sera. Its hydrophilic C0HC medium uses a gradient-density matrix to combine depth filtration and high solids capacity in a scalable disposable Pod. The filter medium contains cellulose and inorganic filter aid, while glass-fiber-reinforced polypropylene forms structural components. The process-scale module provides 1.1 m² of filtration area in a self-contained unit measuring 32 cm high by 62 cm long. Maximum differential pressure is 2.1 bar at 25 °C in either direction and 1 bar at 80 °C in the forward direction; maximum inlet pressure is 3.5 bar at 25 °C and 1 bar at 80 °C. A modular Pod installation scales from approximately 5 L to 12,000 L or more by changing the number and format of filters. Disposable adapters and manifolds simplify connection to adjacent unit operations, while the self-contained construction limits operator exposure to biohazards. The system eliminates a separate filter housing, clean-in-place cycle, maintenance, and cleaning validation. Low hold-up volume helps preserve product yield, and the compact footprint supports installation in limited process space. The unit can receive one 60-minute autoclave cycle at 123 °C. The bacterial-endotoxin level is below 0.25 EU/mL after aqueous extraction.
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