Merck, P350-05, Porcine Coronary Artery Smooth Muscle Cells: PCASMC (Cryovial)

General description
Lot specific orders are not able to be placed through the web. Contact your local sales rep for more details.

PCASMC were used to investigate the role of c-Jun in smooth muscle proliferation, and to show that c-Jun inhibition abrogates smooth muscle cell growth and intimal thickening after arterial injury (Khachigian, 2002). PCASMC were also used to develop poly (l-lactide-co-caprolactone) nanofibrous scaffold material with potential for tissue engineering (Dong, 2008).

Characterization: positive for smooth muscle cell specific alpha-actin expression.
Application
vascular research, supply of blood to heart muscle
Biochem/physiol Actions
Artery
Preparation Note
2nd passage, >500,000 cells in Porcine Smooth Muscle Cell Basal Medium that contains 10% FBS and 10% DMSO
Can be cultured at least 16 doublings

Please refer to the PCASMC Culture Protocol.
Other Notes
Porcine Smooth Muscle Cell Basal Medium that contains 10% FBS and 10% DMSO