Merck, P3558-1KG, Paraplast®

General description
Paraplast® is a paraffin–polyisobutylene mixture for tissue embedding and infiltration. It is a refined combination of highly purified paraffin-containing plastic polymers of regulated molecular weights. It produces minimal tissue compression and wrinkle-free sections and cuts to 4 μm thickness with excellent ribbon continuity.
Paraplast® tissue embedding media are made from highly purified wax combined with plastic polymers for tensile strength and elasticity. Paraplast provides rapid infiltration during processing as well as great compression resistance during sectioning for preserved morphology and thin, distortion-free sections.
Our range of Paraplast products improve the elasticity of brittle, difficult-to-cut tissues making it easier to produce excellent, wrinkle-free sections.
Application
Paraplast® has been used for tissue embedding and in the following applications:to screen major groups of vertebrates for the presence of cardiac smooth muscle and its phylogenetic distribution in terrestrial and aquatic turtles
to study the relationship between membrane impedance and dendrite length of hippocampal neurons
to compare the regenerative properties of human stem cells of the apical papilla as an alternative to other dental stem cells

Features and Benefits
Produces minimal tissue compression and wrinkle-free sections, and cuts to 4 μm thickness with excellent ribbon continuity.
Higher melt viscosity and lower permeability to water vapor creates better adhesion and a more pliable, flexible film.
Optimal infiltration and embedding for high-quality sections.
Great compression resistance and ribbon continuity.
Remarkable morphology preservation and distortion-free sections.

Other Notes
Double filtered paraffin wax in pellet form.
Legal Information
Paraplast is a registered trademark of Leica Biosystems