Merck, PHL89159-25MG, Apigenin

Name: Apigenin
Brand: Merck
SKU: PHL89159-25MG

Size:25 mg, 4′, 5, 7-Trihydroxyflavone, 5, 7-Dihydroxy-2-(4-hydroxyphenyl)-4-benzopyrone, phyproof® Reference Substance

Catalog Number: PHL89159-25MG

Pricing

Send an RFQ.

View RFQ List

Category

pH Standards

Pack Size25 mg

TagsAnalytical Chemistry Reference Materials Phytochemical Standards

CollectionsMerck Certified Reference Materials: CRMs for Calibration, QC & Instrument Validation Merck Cell Culture Supplements & Reagents: Complete Solutions for Research & Bioproduction Merck Roche Life Science Products for PCR, RT‑PCR & Nucleic Acid Purification

Description

General description
This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG
Biochem/physiol Actions
A plant flavonoid that has been found to inhibit cell proliferation by arresting the cell cycle at the G₂/M phase. Inhibition of growth through cell cycle arrest and induction of apoptosis appear to be related to induction of p53. Inhibits PMA-mediated tumor promotion by inhibiting protein kinase C and the resulting suppression of oncogene expression. It has also been reported to inhibit topoisomerase I-catalyzed DNA re-ligation and enhance gap junctional intercellular communication.
A plant flavonoid that has been found to inhibit cell proliferation by arresting the cell cycle at the G₂/M phase. Inhibition of growth through cell cycle arrest and induction of apoptosis appear to be related to induction of p53. Inhibitory effects on tumor promotion may also be due to inhibition of kinase activity and the resulting suppression of oncogene expression. It has also been reported to inhibit topoisomerase I catalyzed DNA religation and enhance gap junctional intercellular communication.
Other Notes
This compound is commonly found in plants of the genus: achillea mentha pimpinella primula salvia silybum thymus
Legal Information
phyproof is a registered trademark of PhytoLab GmbH & Co. KG

Specifications

General

NACRES	NA.24
UNSPSC Code	41116107
Beilstein/REAXYS Number	262620
MDL number	MFCD00006831
SMILES string	Oc1ccc(cc1)C2=CC(=O)c3c(O)cc(O)cc3O2
InChI	1S/C15H10O5/c16-9-3-1-8(2-4-9)13-7-12(19)15-11(18)5-10(17)6-14(15)20-13/h1-7,16-18H
InChI key	KZNIFHPLKGYRTM-UHFFFAOYSA-N
grade	primary reference standard
product line	phyproof® Reference Substance
assay	≥95.0% (HPLC)
form	powder
manufacturer/tradename	PhytoLab
mp	>300 °C (lit.)

Ordering

Notice

Unless otherwise stated, the minimum order amount is USD 1,000.
For orders below USD 1,000, an additional handling fee may apply, or we may arrange local delivery / local handover where available.
All quotations are subject to final confirmation, including product availability, lead time, batch information, shipping cost, and applicable export or handling requirements.
For quotation requests, please send an RFQ from website or contact:

[email protected]

Please send inquiries directly to us in the “To” field. Emails sent via BCC, mass mailing, or with unrelated recipients may be automatically filtered and will not be processed.

Merck, PHL89159-25MG, Apigenin

Send an RFQ.

General

Notice

More from Merck.

Sodium chloride

Sodium acetate trihydrate

Methanol

HPTLC plates, Silica gel 60 F₂₅₄

More from Merck.

Sodium chloride

Sodium acetate trihydrate

Methanol

HPTLC plates, Silica gel 60 F₂₅₄