Merck, PHR1067-1G, Carbamazepine

Name: Carbamazepine
Brand: Merck
SKU: PHR1067-1G

Size:1 g, 5H-Dibenz[b, f]azepine-5-carboxamide, Pharmaceutical Secondary Standard; Certified Reference Material

Catalog Number: PHR1067-1G

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Category

Pharmaceutical Reference Standards

Pack Size1 g

TagsChromatography Standards Analytical Chemistry Analytical Chromatography

CollectionsMerck Analytical Chromatography Products & Lab Supplies Merck Cell Culture Supplements & Reagents: Complete Solutions for Research & Bioproduction Merck Roche Life Science Products for PCR, RT‑PCR & Nucleic Acid Purification

Description

General description
Certified pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to in-house working standards.

Carbamazepine is a tricyclic lipophilic compound, with mild anticholinergic activity. It is widely used as an antiepileptic drug for the treatment of simple and complex partial tonic-clonic seizures.
Application
Carbamazepine may be used as a pharmaceutical reference standard for the quantification of the analyte in pharmaceutical formulations using chromatography techniques.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Biochem/physiol Actions
Anticonvulsant; ligand for the GABAA receptor benzodiazepine modulatory site. Sodium channel inhibitor.
Analysis Note
These secondary standards offer multi-traceability to the USP and EP (PhEur) primary standards, where they are available.
Other Notes
Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAA6055 in the slot below. This is an example certificate only and may not be the lot that you receive.

Specifications

General

NACRES	NA.24
PubChem Substance ID	329823092
UNSPSC Code	41116107
EC Number	206-062-7
MDL number	MFCD00005073
InChI	1S/C15H12N2O/c16-15(18)17-13-7-3-1-5-11(13)9-10-12-6-2-4-8-14(12)17/h1-10H,(H2,16,18)
InChI key	FFGPTBGBLSHEPO-UHFFFAOYSA-N
SMILES string	NC(=O)N1c2ccccc2C=Cc3ccccc13
grade	certified reference material
agency	traceable to Ph. Eur. C0450000
API family	carbamazepine
CofA	current certificate can be downloaded
technique(s)	HPLC: suitable
mp	191-192 °C (lit.)
application(s)	pharmaceutical (small molecule)
format	neat
storage temp.	2-30°C
Quality Level	300
Gene Information	human ... SCN10A(6336), SCN11A(11280), SCN1A(6323), SCN2A(6326), SCN3A(6328), SCN4A(6329), SCN5A(6331), SCN7A(6332), SCN8A(6334), SCN9A(6335)

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Merck, PHR1067-1G, Carbamazepine

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