Merck, PHR1963-50MG, (+)-Catechin

General description
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

(+)-Catechin is a flavan-3-ol, that belongs to the family of polyphenolic flavonoids, called catechins. Found in green tea, it shows many health benefits, such as anti-oxidant, anti-inflammatory, anti-proliferative, and anti-platelet activity.
This compound can be found as a component in plants of the genus: cinnamomum, crataegus, eucalyptus, hypericum, primula
Application
This pharmaceutical secondary standard can also be used as follows:

• Development of an ultra-high performance liquid chromatography-triple-quadrupole tandem mass spectrometry (UHPLC-MS-MS) method for the simultaneous determination of eight catechins and four theaflavins in three types of tea samples
• Separation and estimation of six tea catechins and caffeine by an UHPLC method coupled to a UV detector from green tea samples
• Simultaneous analysis of five naturally occurring catechins by an isocratic HPLC method
• Infrared-assisted extraction (IRAE) followed by HPLC separation and quantification of catechin, epicatechin, and procyanidin B2 in grape seed samples
• Analysis of caffeine and catechins from green tea leaves by pressurized liquid extraction (PLE) using ethyl lactate, water, and ethyl lactate + water mixtures

Analysis Note
These secondary standards offer multi-traceability to the USP and EP primary standards, where they are available.
Other Notes
Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
To see an example of a Certificate of Analysis for this material enter LRAC2624 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.