Merck, SAB5702227-100UL, Anti-ABL2 Antibody, clone 2L9C6, Rabbit Monoclonal

General description
This gene encodes a member of the Abelson family of nonreceptor tyrosine protein kinases. The protein is highly similar to the c-abl oncogene 1 protein, including the tyrosine kinase, SH2 and SH3 domains, and it plays a role in cytoskeletal rearrangements through its C-terminal F-actin- and microtubule-binding sequences. This gene is expressed in both normal and tumor cells, and is involved in translocation with the ets variant 6 gene in leukemia. Multiple alternatively spliced transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq, Nov 2009]
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 500-600 of human ABL2 (P42684).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Application
WB