Merck, SAB5702403-100UL, Anti-Cyclophilin B Antibody, clone 7Z4S7, Rabbit Monoclonal

General description
The protein encoded by this gene is a cyclosporine-binding protein and is mainly located within the endoplasmic reticulum. It is associated with the secretory pathway and released in biological fluids. This protein can bind to cells derived from T- and B-lymphocytes, and may regulate cyclosporine A-mediated immunosuppression. Variants have been identified in this protein that give rise to recessive forms of osteogenesis imperfecta. [provided by RefSeq, Oct 2009]
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 100-200 of human Cyclophilin B (P23284).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Application
WB