Merck, SAB5702639-100UL, Anti-FHIT Antibody, clone 3Z1U4, Rabbit Monoclonal

General description
This gene, a member of the histidine triad gene family, encodes a diadenosine 5',5'''-P1,P3-triphosphate hydrolase involved in purine metabolism. The gene encompasses the common fragile site FRA3B on chromosome 3, where carcinogen-induced damage can lead to translocations and aberrant transcripts of this gene. In fact, aberrant transcripts from this gene have been found in about half of all esophageal, stomach, and colon carcinomas. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Oct 2009]
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human FHIT (P49789).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Application
WB